Protecting Photoreceptor Cells
Researchers at the department of pharmacology at Case Western Reserve University School of Medicine have found a “gentle” combination of FDA-approved medications that may help protect photoreceptor cells against damage. Photoreceptor cells are found in the back of the retina and allow us to see contrast, shade, color, and definition. These cells can be damaged by bright lights as well as by retina disorders such as macular degeneration.
In this most recent study, researchers employed the method of systems pharmacology – an approach that seeks to understand how various medicines impact different systems of the body – to determine how a multi-medication approach may help address damage to the retina on several fronts. Focusing on four medications, bromocriptime, metroprolol, doxazosin, and tamsulosin, researchers were able to protect mice from retinal damage with greater success than one medicine at a time, even when those singular medicines were given at higher doses. While not yet studied in humans, this research may indicate that a specific regimen of low-dose medications may actually be more effective at combatting retinal damage than current single-medication approaches in the treatment of macular degeneration and other sight-stealing disorders.
The San Diego retina specialists at California Retina Associates utilize the most advanced treatment options to help protect our patients from vision loss. If you are experiencing any of the symptoms of a retinal disorder, please contact us online or by calling (619) 425-7755 or (760) 352-7755 to schedule an examination today.